The implementation of civil aircraft avionics functions usually involves multiple systems. During the design process, it is also necessary to consider safety at the same time. The comprehensive design of system architecture is becoming increasingly complex. However, the current design of civil aircraft avionics architecture lacks safety considerations, resulting in insufficient design. In view of this issue, a safety-oriented architecture design process for civil aircraft systems is proposed. The architecture design is carried out at the requirements, functions, logic, and physical hierarchical levels, with unified definition and decomposition of architecture elements. Vertical mapping relationships between each layer of models are established, implemented comprehensive functional analysis and architecture design for multi-system integration. Finally, perform fault tree analysis on the architecture model by traversing physical architecture faults. The practical results of attitude display architecture design indicate that this method can effectively handle the architecture design of complex systems, improve the overall safety and engineering efficiency of the system, and promote continuous optimization of system quality.