Lighting system is an important branch of civil aircraft, which not only plays a significant role in the safety and performance of the aircraft and the work efficiency of the flight crew, but also is an important component of evaluating aircraft advancement and comfort for passengers. Generally, lighting system is consisted of cockpit lighting system, cabin lighting system, cargo and service area lighting system, exterior lighting system and emergency lighting system. To verify the compliance of lighting system to CCAR 25. 1309 during the system developing process, the methods for system safety assessment proposed by SAE ARP 4761 is generally followed. Based on the methods of security assessment, this article takes lighting system as the object. In the design phase, the safety design goals were determined and the system architecture was put forward through preliminary safety assessment. The safety design goals proposed earlier were verified by using a variety of methods during the verification period. In addition, the specific methods of safety analysis assessment during the whole development process were discussed, which can provide reference for the safety analysis of civil aircraft.