In order to work well on the dispatching, operation control and monitoring at high-plateau airport, the round-trip flight of Chengdu to Hongyuan was researched as sample. Through researching on aspects of Hongyuan airport’s geographical environment, climate characteristics, airdrome support capability, and operation characteristics, it concluded the dispatching fuel policy of this airport. And then within the scope of the civil aviation regulations it made out the related procedures for the one-engine failure to float down and cabin depression to descent in emergency. Finally it teased out the key factors for flight safety to reach the purpose of solving difficulties on operational control. Above all, this conclusion has reference significance to the same type of airports and airlines.