With the development of high lift devices, hinged droop-nose with simple structure is used inside the wing of the new commercial aircraft. Compared to the most common slat, it can reduce drag and noise, improve lift-drag ratio and so on. In this paper,aerodynamic optimization design and computational investigation on the hinged droop-nose airfoil for large aircraft is studied. First, a two-dimensional airfoil for hinged droop-nose is designed.Then airfoil aerodynamic optimization through iSIGHT platform is conducted. The low speed aerodynamic characteristics of the hinged droop-nose airfoil are analyzed and the best airfoil is obtained. At last, compared with slat in terms of aerodynamic performance,and so the feasibility of the hinged droop-nose is verified.